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vol.73 número1DETERMINACIÓN DEL SEXO FETAL MEDIANTE ADN LIBRE FETAL EN PLASMA MATERNOFACTORES PRONÓSTICOS DEL CARCINOMA DUCTAL IN SITU DE MAMA índice de autoresíndice de materiabúsqueda de artículos
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Revista chilena de obstetricia y ginecología

versión impresa ISSN 0048-766Xversión On-line ISSN 0717-7526

Resumen

TREUER P, Carlos et al. LONGITUD CERVICAL Y FIBRONECTINA EN EL SÍNTOMA DE PARTO PREMATURO. Rev. chil. obstet. ginecol. [online]. 2008, vol.73, n.1, pp.31-34. ISSN 0048-766X.  http://dx.doi.org/10.4067/S0717-75262008000100006.

Background: In Chile the preterm labor is the main cause of perinatal morbidity and mortality. Objective: To evalúate the clinical utility of the cervical length and fibronectin determination in predicting preterm delivery. Method: A prospective observational and transactional study was made, in 86 patients with preterm labor symptoms and gestational age between 22 and 34 weeks. The study group included patients with labor and delivery within a week of admission. From each patient a cervico-vaginal specimen was obtained to measure fibronectin and transvaginal ultrasonographic evaluation of the uterine cervix. Results: From 86 patients admitted to the study, thirteen had preterm labor (15%). The ROC curve showed an área under curve for cervical length of 0.475 and sensitivity 31 % (4/13), specificity 96% (70/73), positive predictive valué 57%(4/13), negative predictive valué 88% (70/79), positive relative risk was 5.0, and the negative relative risk 0.47 (p=0.014); for fibronectin was 0.92 and sensitivity 77% (10/13), specificity 90% (66/73), positive predictive valué 59% (10/17), negative predictive valué 96% (66/69), positive relative riskof 13.48, negative relative risk 0.43 (p=0.014). Conclusión: In patients with premature labor symptoms, the cervical lengths none shortened and negative fibronectin result were associated with a low risk of having a preterm labor. Positive fibronectin was a better predictor of premature birth in a week of admission and the cervical length was the best in ruling out the occurrence of a premature birth

Palabras clave : Preterm labor; fetal fibronectin; uterine cervix; transvaginal ultrasonography.

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