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vol.75 número2MORFOMETRÍA DEL NUCLEOLO EN LA DIFERENCIACIÓN CELULAR DEL EPITELIO MAMARIODETERMINACIÓN DEL SEXO FETAL EN EL PRIMER TRIMESTRE DE LA GESTACIÓN: ESTUDIO PROSPECTIVO índice de autoresíndice de materiabúsqueda de artículos
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Revista chilena de obstetricia y ginecología

versión impresa ISSN 0048-766Xversión On-line ISSN 0717-7526

Resumen

REYNA VILLASMIL, Eduardo et al. CONCENTRACIONES DE INTERLEUCINA-2 EN PACIENTES CON PREECLAMPSIA A TÉRMINO Y PRETÉRMINO. Rev. chil. obstet. ginecol. [online]. 2010, vol.75, n.2, pp.112-116. ISSN 0048-766X.  http://dx.doi.org/10.4067/S0717-75262010000200007.

Background: There are contradictory results about interleukin-2 (IL-2) concentrations in preeclamptic patients and is unknown if there are differences in concentrations at the time of diagnosis. Objective: To compare concentrations of IL-2 in term and preterm preeclamptic patients. Method: Fifty patients were selected. Twenty preterm preeclamptic patients (group A) and thirty term preeclamptic patients (group B) were selected. Blood samples for IL-2 were collected in all patients before labor and immediately after diagnosis of preeclampsia. Results: There were not signifcant differences related to a maternal age, body mass index and mean values of systolic and diastolic blood pressure at the moment of collecting samples. There were signifcant differences between groups in gestational age. There also was not signifcant difference in IL-2 concentrations in the study group (67.5 ± 31.8 pg/ml) and patients in control group (69.6 ± 28.5 pg/ml). There was not signifcant correlation between interlukin-2 and mean values of systolic and diastolic blood pressure. Conclusion: Preeclamptic patients with preterm pregnancies presented similar interleukin-2 concentrations when compared to term preeclamptic patients at the time of diagnosis. The fnding of this research suggests a lack of activation of T-lymphocytes in preeclamptic patients.

Palabras clave : Interleukin 2; preclampsia; cytokines.

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