SciELO - Scientific Electronic Library Online

 
vol.83 número4Adenocarcinoma sincrónico de alto grado de endometrio y ovario; a propósito de un caso clínicoQuistes subamnióticos en el contexto de restricción de crecimiento fetal índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google

Compartir


Revista chilena de obstetricia y ginecología

versión impresa ISSN 0048-766Xversión On-line ISSN 0717-7526

Resumen

BUENO-GONZALEZ, Ma del Mar et al. Pioderma gangrenoso vulvar: revisión de la literatura a propósito de un caso causado por rituximab. Rev. chil. obstet. ginecol. [online]. 2018, vol.83, n.4, pp.402-407. ISSN 0048-766X.  http://dx.doi.org/10.4067/s0717-75262018000400402.

Pyoderma Gangrenosum is a chronic necrotizing inflammatory disease that belongs to the spectrum of Neutrophilic Dermatoses. Histologically, it is characterized by a dense inflammatory infiltrate of non-infectious neutrophils. Etiology is not yet well defined. It is usually associated with systemic diseases such as inflammatory bowel disease, rheumatoid arthritis or hematological diseases. It presents pathergy phenomenon and usually respond satisfactorily to immunosuppressive treatments.

There have been published only 15 cases of vulvar pyoderma gangrenosum associated with the use of rituximab. We present a new case, which occurred in a 37-year-old woman on maintenance treatment with rituximab for a follicular non-Hodgkin's lymphoma.

Rituximab (MabThera®) is an antibody that recognizes the CD20 molecule, which is a non-glycosylated protein that is expressed on the surface of B lymphocytes. This drug has been used for the treatment of different rheumatic diseases in recent years.

Palabras clave : skin diseases; pyoderma gangrenosum; rituximab; adverse effects.

        · resumen en Español     · texto en Español     · Español ( pdf )