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vol.85 suppl.1Case report: multidisciplinary management in case of 31 weeks pregnant woman and COVID 19 infection with severe disease presentation.Interruption of pregnancy in times of COVID-19, Carlos Van Buren Hospital, Valparaiso: about 6 clinical cases author indexsubject indexarticles search
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Revista chilena de obstetricia y ginecología

Print version ISSN 0048-766XOn-line version ISSN 0717-7526


SABAT V, Scherezade et al. Elevated liver enzimes induced by COVID-19 in pregnancy. Rev. chil. obstet. ginecol. [online]. 2020, vol.85, suppl.1, pp.S101-S105. ISSN 0048-766X.


Approximately 3-5% of women present alterations of hepatic enzymes during pregnancy. Under the new circumstances that the world is facing with the SARS-COV2 pandemic, a new etiology for hepatic enzyme alterations has risen. The severe acute respiratory syndrome that the novel coronavirus causes is responsible for hepatic enzyme alterations in 2 to 11% of the sick population that did not have a previous underlying hepatic condition. Furthermore, hepatic enzyme alterations in pregnant women infected with SARS-COV2 presents in up to 30% of the cases. An infrequent presentation of SARS-COV2 is presented as our clinical case.

Clinical Case:

A 36-year-old patient with a 20+6 week pregnancy presents abdominal pain, jaundice and choluria. General blood workup shows elevated transaminases. The abdominal ultrasound revealed a thin bile duct. Acute and chronic hepatitis etiologies were discarded. Finally, a PCR of COVID-19 was solicited, which turned out to be positive.


After an exhaustive study to determine the etiology of the elevated transaminases, the hepatic alterations were attributed to SARS-COV2 infection. A conservative management was adopted, with outpatient follow-up with liver testing every two weeks. The patient progresses with a stable steady decline in hepatic enzyme levels, and one-month post hospital discharge, her transaminases had reached normal values. Based on this clinical case, after ruling out frequent etiologies for elevated transaminases during pregnancy, it seems reasonable to request a PCR for COVID-19, since it could be a rare presentation of SARS-CoV-2.

Keywords : Pregnancy; SARS-CoV-2; elevated liver enzymes; liver disease.

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