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Revista chilena de radiología

versão On-line ISSN 0717-9308

Resumo

LADRON DE GUEVARA H, David et al. ENFERMEDAD DE PAGET VERTEBRAL DETECTADA POR CINTIGRAMA OSEO MDP-TC99M: SIGNO DEL "RATON MICKEY". Rev. chil. radiol. [online]. 2003, vol.9, n.4, pp.201-203. ISSN 0717-9308.  http://dx.doi.org/10.4067/S0717-93082003000400007.

Paget disease (PD) is a benign bone disease affecting 3% of the population over 40 years of age. This disease produces thikening and deformity of bone caused for excessive and abnormal remodeling, mainly in axial skeleton. Because to the pathologic characteristics and hypervascularity of lesions, bone scan shows generally intense tracer uptake wherever it localizes. Scintigraphic lesion can have a very particular shape in some cases of skull, jaw and spine involvement. We report the clinical case of a 70 years old man with prolonged back pain and a L1 lesion characteristic of PD in bone scan ("Mickey mouse" sign). Radiography and CT were compatible, and biopsy confirmed PD diagnosis. This scintigraphic sign was reported for first time by Estrada et al in 1993, and shows high specificity for vertebral PD diagnosis.

Palavras-chave : Mickey mouse sign; Paget´s disease; Spine.

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