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Revista chilena de radiología

On-line version ISSN 0717-9308


HERRERA A, Carolina et al. Microcalcifications and punctate echogenic foci, how well do we know what we are seeing?. Rev. chil. radiol. [online]. 2017, vol.23, n.4, pp.143-150. ISSN 0717-9308.

The presence of microcalcifications in thyroid nodules is a very specific sign of malignancy, as it corresponds to Psammoma bodies. There are not enough studies that demonstrate a correlation between their histological presence and their actual ultrasound appearance.

Materials and Methods:

All nodules larger than 3 cm punctured at the Universidad Católica Clinical Hospital between 2010-2015 were selected, and the sonographic appearance was classified according to the presence of 3 types of echogenic foci according to a stricter definition than usual. The above was correlated with findings in biopsies.


44 nodules corresponded to papillary thyroid cancer. There was a statistically significant relationship between a new ultrasound definition of the microcalcifications (punctate echogenic foci) and the histological presence of psamomma bodies.


There would be a good correlation between a stricter definition and the actual presence of microcalcifications in histology, improving the high rate of over diagnosis recently noticed by some authors.

Keywords : Thyroid; Ultrasound; Microcalcifications; Psamomma bodies.

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