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vol.27 issue3Morphological Study of Myoneural Interaction between the Levator Labii Superioris Muscle and its Motor Nerve in Rats author indexsubject indexarticles search
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International Journal of Morphology

On-line version ISSN 0717-9502

Abstract

PEREIRA, Marli Aparecida dos Santos et al. Morphometry and Quantification of the Myenteric Neurons of the Cecum of Rats (Rattus norvegicus) Submitted to Experimental Chronic Alcoholism. Int. J. Morphol. [online]. 2009, vol.27, n.3, pp.619-626. ISSN 0717-9502.  http://dx.doi.org/10.4067/S0717-95022009000300001.

Morphometric and quantitative analyses were accomplished to study the effects of the consumption of alcohol above the size and density of the myenteric neurons of cecum of rats. Ten rats with 90 days were divided in the groups: control (C), and alcoholic (A). After 120 days of treatment with ethanol the cecum of both groups were collected, submitted it prepared of membranes that after carried out to Giemsa´s technique, permitted to evaluate the neuronal density, in an area of 13.44mm2, and measure the cell body area of 300 neurons by group. The alcoholic rats presented an increase in the number of small neurons and a reduction of the big and medium neurons. The neuronal density verified in alcoholic rats was significantly reduced regarding the controls rats, however, that reduction left of be statistically significant when was projected the neuronal density for the total area of cecum, since the macroscopic observation showed that the alcoholic rats presented a cecum dilated. The alcoholism induced a significant reduction in the final body weight of the rats of the GA, provoked enlargement of cecum of the rats causing to a big dispersion neuronal. The enlargement of cecum of the alcoholic rats is probably associated with the functional alterations of the myenteric neurons that have repercussions in the tone of the intestinal smooth muscle.

Keywords : Alcoholism; Cecum; Myenteric neurons.

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