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International Journal of Morphology

versión On-line ISSN 0717-9502

Resumen

ARAUJO, Eduardo José de Almeida et al. Atrophy of the Nitrergic Myenteric Neurons in the Descending Colon Rats Submitted to Protein and Vitamin Deficiency. Int. J. Morphol. [online]. 2009, vol.27, n.3, pp.939-945. ISSN 0717-9502.  http://dx.doi.org/10.4067/S0717-95022009000300047.

Effects of protein and B-complex vitamin deficiency were assessed with respect to the morphometry of myenteric neurons in the descending colon of adult rats. Sixteen animals were divided into two groups: Control Group (CG, n=8) and Experimental Group (EG, n=8). The CG received 22% protein chow and the EG received 4% protein chow for 120 days. The descending colon was submitted to NADH- and NADPH-diaphorase technique in order to evidence nervous cells in the whole mounts preparations. In the EG, NADH-d positive neurons presented reduced nuclei, while NADPH-d positive neurons showed atrophy of the soma area (~41.7%) inducing an increase of the proportion occupied by the nucleus inside in the soma of these cells.

Palabras clave : Malnutrition; Large intestine; Enteric nervous system; Myenteric plexus; Neural plasticity.

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