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International Journal of Morphology

versión On-line ISSN 0717-9502

Resumen

TAPIA E, Oscar; ROA S, Juan Carlos; MANTEROLA D, Carlos  y  BELLOLIO J, Enrique. Colon and Rectum Cancer: Morphological and Clinical Description of 322 Cases. Int. J. Morphol. [online]. 2010, vol.28, n.2, pp.393-398. ISSN 0717-9502.  http://dx.doi.org/10.4067/S0717-95022010000200010.

The colorectal cancer (CRC) is currently the fourth cause of cancer death in Chile. Its incidence, however, is continuously increasing in our population. The aim of this study is to describe morphological and clinical aspects of patients resected CRC. Retrospective cohort study. We studied 322 patients operated on for CRC between 1987 and 2003 in the Hernan Henriquez Aravena Hospital of Temuco. The clinical and morphological variables studied (all analyzed for subgroups of subjects with tumors of the colon and rectum) were age, gender, tumor location, tumor size and shape, level of infiltration, histological type, histological differentiation grade and tumor involvement lymph node. We used descriptive statistics and analytical, using Pearson chi-square and Fisher exact tests for categorical variables and T-test for continuous variables. The median age was66 years, with average age of the right colon tumors (RC), transverse (TC), left (LC) and rectum was 62.2, 64.6, 64, and 64.4 years respectively (p = 0.53). In RC and LC were observed 57% and 47% of women, respectively (p <0.05). 69% of the cases corresponded to tumors of the colon (24% RC, 4% TC and 41% LC) and 31% to cancer of the rectum. The average tumor size was 67.2 ± 33.1 mm RC, 53.5 ± 19.7 mm. TC, 44.1 ± 22.3 mm LC and 41.5 ± 17.5 mm in the rectum (p <0.001). On RC as Bormann type I was observed in 57% while the LC annular and ulcerative lesions 45% CI. We found 75% of moderately differentiated tumors, corresponding to 82% adenocarcinomas, 16% and 2% mucinous adenocarcinoma cell carcinoma signet-ring. 76% were T3 and T4 tumors. We found lymph node tumor involvement in 39% of which 95% were T3-T4 tumors. We checked at the regional level for patients with CRC clinical and morphological variables described in the literature.

Palabras clave : Colorectal cancer; Colon cancer; Rectal cancer.

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