SciELO - Scientific Electronic Library Online

 
vol.29 issue3Observations on Estrus as Monitored by Receptivity to Mating Activity and Pattern of Vaginal Exfoliates In Trypanosoma brucei ­ Infected WAD Goat does Synchronized with Estrumate®Histological Study of Digestive Tract of the Neón Cardenal Paracheirodon axelrodi (Characidae) author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

Share


International Journal of Morphology

On-line version ISSN 0717-9502

Abstract

MONTIEL-EULEFI, Enrique et al. Pericytes: New Approaches in Regenerative Therapy, Cerebrovascular Pathology and Cancer. Int. J. Morphol. [online]. 2011, vol.29, n.3, pp.769-781. ISSN 0717-9502.  http://dx.doi.org/10.4067/S0717-95022011000300017.

Mesenchymal stem cells are a multipotent population of cells that have extensive capacity for differentiation, plasticity and immunosuppressive potential, making them an important tool in cell-based therapies. According to their potential, it has been determined that perivascular cells have stem cell characteristics of great clinical potential, however, the biological properties that lead to their differentiation are less understood. Recent advances in understanding the relationship between pericytes and mesenchymal stem cells pose tissue-specific functions, as well as their potential therapeutic use in ischemia, such as cerebro-vascular and a better understanding of the pathological tumor vascularization. Despite the growing acceptance that perivascular cells are related, or that they are mesenchymal stem cells, there is little experimental evidence to show the differentiation of pericytes in different cell types (Feng et al., 2010). In this review we document the biological basis of pericytes that support their use in regenerative therapy.

Keywords : Pericytes; Regenerative therapy; Cerebrovascular disease; Cancer.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License