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International Journal of Morphology

On-line version ISSN 0717-9502

Abstract

RIVERA MARTINEZ, César Andrés. 4NQO Carcinogenesis: A Model of Oral Squamous Cell Carcinoma. Int. J. Morphol. [online]. 2012, vol.30, n.1, pp.309-314. ISSN 0717-9502.  http://dx.doi.org/10.4067/S0717-95022012000100055.

The experimental oral carcinogenesis induced by the chemical 4-nitroquinoline 1-oxide (4NQO) is one of the most frequent in the study of squamous cell carcinoma of the oral cavity (CCEC). The clear advantage is that the model is very similar to the physiological process of malignancy. The model has clear benefits by and is suitable for applications in therapeutic research.

Keywords : 4NQO; Experimental carcinogenesis; Oral squamous cell carcinoma; Tongue.

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