SciELO - Scientific Electronic Library Online

 
vol.33 issue3A Study on the Structure and Morphologic Development of Calcaneal Tendon and Triceps Surae Muscle in Human Fetuses during the Fetal Period and the Evaluation of Clinical Importance of Calcaneal TendonThe Radial Carpal Extensor Muscles and their Clinical Significance: A Review of the Literature author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


International Journal of Morphology

On-line version ISSN 0717-9502

Abstract

HEYDARI, Leila et al. Effects of Ovarian Varicose Vein on Mitochondrial Structure, Malondialdehyde and Prooxidants: Antioxidants Balance in Rat Ovaries. Int. J. Morphol. [online]. 2015, vol.33, n.3, pp.930-935. ISSN 0717-9502.  http://dx.doi.org/10.4067/S0717-95022015000300020.

Oxidative stress is increased in varicose veins. Many studies have implicated oxidative stress in the pathogenesis of infertility causing diseases of the female reproductive tract. The aim of this study was to determine whether varicocele can cause raised levels of reactive oxygen species and denaturation of mitochondrial structure in ovaries of female rats or not. In each experimental study, 15 weaning-age female rats were divided equally in 3 groups: Unilateral Varicose Vein (A), Sham (B) and Control (C) groups. Mitochondrial structure and malondialdehyde levels as a product of lipid peroxidation and Prooxidants-Antioxidants Balance were evaluated 60 days after intervention in proestrus stage. Comparisons between groups were made by the measured test. After 2 months, our results showed that mitochondrial structure ultra-structurally was denatured with histologic examination, malondialdehyde and prooxidants-antioxidants balance levels of left ovaries increased significantly in varicocele group compared to control and sham groups (P0.05). In the right side, malondialdehyde increased significantly, but in prooxidants-antioxidants balance levels, there is no significant differences between groups. The data of control and sham groups were the same. These findings may support the concept that increased levels of malondialdehyde and PAB in varicocele may cause negative effects on fertility, so using antioxidants maybe useful.

Keywords : Female varicocele; Proestrus phase; Mitochondrial structure; Malondialdehyde; Prooxidants-Antioxidants Balance.

        · abstract in Spanish     · text in English     · English ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License