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International Journal of Morphology

On-line version ISSN 0717-9502

Abstract

TOLEDO, Gustavo Lopes et al. Ppe Tube Filled With Autologous Fat in the Repair of Peripheral Nerve: A New Proposal. Int. J. Morphol. [online]. 2016, vol.34, n.3, pp.1151-1157. ISSN 0717-9502.  http://dx.doi.org/10.4067/S0717-95022016000300055.

This study proposes the use of a porous polyethylene (PPE) tube as the conductive element in the regeneration in the sciatic nerve sectioning and evaluates the use of fill with autologous fat. The subject was divided randomly into five groups, 3 control and 2 experimental (PPE tube graft with/ without autologous fat). Each group was selected for functional, histological and morphometric evaluation of the sciatic nerve. Functional analysis of the sciatic nerve occurred through the "footprint" values near -100 refer sectioned sciatic nerve, near 0 (zero) refer to control group. On histological analysis of the experimental groups lots of dense connective tissue replacing nerve tissue was observed. In morphometric analysis the group EGPGf got higher performance in all of variables. The use of PPE has shown promise in nerve regeneration with favorable results when associate with fat as a trophic factor in the regeneration.

Keywords : Rat sciatic nerve; Axonal regeneration; Porous polyethylene pipe.

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