SciELO - Scientific Electronic Library Online

 
vol.34 issue4Liver: Seven Hepatic SegmentsA Radiological Investigation on the Hand Development in Human Fetuses Throughout the Fetal Period and an Evaluation Performed in Terms of its Clinical Importance Hand Development author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


International Journal of Morphology

On-line version ISSN 0717-9502

Abstract

ALISTER, Juan Pablo et al. Stem Cells in Human Cranio-Maxillo-Facial Reconstruction. Int. J. Morphol. [online]. 2016, vol.34, n.4, pp.1531-1538. ISSN 0717-9502.  http://dx.doi.org/10.4067/S0717-95022016000400056.

The purpose of this study was to evaluate the evidence regarding the use of reconstructive techniques in the craniofacial area associated with the use of stem cells in humans. A systematic review of the literature was conducted in the databases Medline, ScienceDirect, EMBASE, TripDatabase, LILACS between March 2004 and March 2016 with eligibility criteria and defined search strategy. The selection of articles was done by two researchers independently and when they presented discordance, a third researcher made the selection. We found a total of 382 articles, made a selection of articles, removed duplicates, experimental studies in animals and selection according to analysis of abstracts, we selected 14 articles with reconstructive procedures in the craniofacial area associated with stem cells. There is limited quality evidence regarding the use of stem cells in the craniofacial reconstruction in humans. With the exception of one study (clinical trial of low level of evidence), all correspond to series or report of cases, with which it is not possible to recommend its use in reconstructive procedures. It is necessary to carry out studies of sustainable evidence with the use of stem cells that allow to identify its real performance when compared with other surgical techniques.

Keywords : Stem cells; Reconstruction; Tissue engineering; Craniofacial surgery.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License