SciELO - Scientific Electronic Library Online

vol.36 issue1Evaluation of the Anti-inflammatory Activity of Chilean Propolis on Histological Sections of Mouse EarsSomatotype of Taekwondo Athletes at the Regional Training Center in Valparaíso, Chile author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


International Journal of Morphology

On-line version ISSN 0717-9502


QIN, Haiyan et al. Surgical Treatment of a Massive Neurofibroma of the Head and Neck in a Patient with Neurofibromatosis Type 1: A Case Report. Int. J. Morphol. [online]. 2018, vol.36, n.1, pp.194-200. ISSN 0717-9502.

Neurofibromatosis type 1 (NF1) is a rare autosomal dominant neurogenetic disease with variable clinical manifestations, which are primarily manifested as neurofibromas, café-au-lait macules (CALMs) and skeletal deformities. Although generally benign, expansile neurofibromas that are characteristic of NF1 readily lead to disturbing deformities. It is often difficult to surgically extirpate a tumor that involves these important tissues or organs. We report a rare case of a patient with neurofibromatosis Type 1. The patient presented with a congenital giant scalp neurofibroma and CALMs in the occipito-cervical region, in addition to ear and occipital deformities. We performed a challenging surgical intervention (a near-total resection) to reduce the tumor burden and rehabilitate the appearance and function of the patient while preserving the intracranial tissue structure. Here, we review this case and analyze the clinical manifestations, diagnosis and management of NF1.

Keywords : Neurofibromatosis Type 1; Occipital bone defect; Ear deformity; Surgical treatment..

        · abstract in Spanish     · text in English     · English ( pdf )