SciELO - Scientific Electronic Library Online

vol.37 issue4Profile and Reference Values for Body Fat and Skeletal Muscle Mass Percent at Females, Aged from 18.0 to 69.9, Measured by Multichannel Segmental Bioimpedance Method: Serbian Population StudyRelationships Between the 2D:4D Digit Ratio, Waist Circumference, Hand Preferences, Weight, Height, Waist-to-Height Ratio and BMI in a Turkish Population author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google


International Journal of Morphology

On-line version ISSN 0717-9502


ROSAS-C, Carlos et al. Calreticulin Expression in Canine Placenta. Int. J. Morphol. [online]. 2019, vol.37, n.4, pp.1294-1298. ISSN 0717-9502.

The placenta is an embryonic organ present in mammals, whose main functions are the exchange of nutrients and gases and to protect the fetus from potential immune damage mediated by paternal and maternal allogeneic differences in the Major Histocompatibility Complex. Several proteins associated with its function have been described, being Calreticulin one of them. Although there are studies on the presence of Calreticulin in human placenta, there are no reports of this protein in canine placenta. Samples from canine placenta were obtained, proteins extracted and Calreticulin was subsequently detected by western blot and immunohistochemistry. The results showed the presence of Calreticulin in canine placenta with an apparent molecular weight of 60 kDa, in agreement with the results from other authors. The immunohistochemical analysis showed that canine Calreticulin is present mainly in the trophoblast of the villi, and there is no difference in its localization when compared with a blood-filled placenta such as human one, despite its morphological and histological differences. We also propose a standardized protocol for the extraction of Calreticulin from placenta, given its abundant expression in this organ. Future studies are aimed at elucidating possible roles of this protein in placenta.

Keywords : Calreticulin; Placenta; Trophoblast.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )