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International Journal of Morphology

On-line version ISSN 0717-9502

Abstract

SANZANA-CUCHE, R; FERNANDEZ, E; LEIVA, A. P  and  ROSAS, C. C. Calreticulin Expression Analysis in Small Saphenous Vein. Int. J. Morphol. [online]. 2020, vol.38, n.1, pp.182-185. ISSN 0717-9502.  http://dx.doi.org/10.4067/S0717-95022020000100182.

Calreticulin (CRT) protein, has been identified in the endoplasmic reticulum (ER) and lately in the extracellular matrix (ECM) of predentine and arteries. It is responsible for different extracellular functions, such as cell adhesion, ECM regulation, and the prevention of thrombosis. The aim was to identify the presence of CRT in ECM of small saphenous vein. A sample of small saphenous vein from a male specimen was extracted and then processed by histological and immunohistochemical assays to identify its presence. The presence of CRT in the ECM of the small saphenous vein was observed by immunohistochemical techniques. The presence of CRT in the small saphenous vein ECM, indicates that CRT have extracellular functions in this area, however, more precise studies are necessary to determine its main functions.

Keywords : Calreticulin; Small saphenous vein; Extracellular matrix.

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