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vol.53 número2COMPARISON OF VOLATILE COMPONENTS FROM MARCHANTIA CONVOLUTA OBTAINED BY MICROWAVE EXTRACTION AND PHYTOSOL EXTRACTIONFORMATION OF METASTABLE VATERITE CRYSTALS IN A POLYMER MATRIX BY GASEOUS DIFFUSION índice de autoresíndice de assuntospesquisa de artigos
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Journal of the Chilean Chemical Society

versão On-line ISSN 0717-9707

Resumo

LIU, CHIA-YUAN et al. CYTOTOXIC CONSTITUENTS FROM THE ROOT WOOD OF FORMOSAN MICHELIA COMPRESSA. J. Chil. Chem. Soc. [online]. 2008, vol.53, n.2, pp.1523-1524. ISSN 0717-9707.  http://dx.doi.org/10.4067/S0717-97072008000200017.

The methanolic extract of the root wood of Michelia compressa (Maxim.) Sargent showed cytotoxicity against MCF-7, NCI-H460 and SF-268 cancer cell lines. Bioassay-guided fractionation of the chloroform-soluble layer led to the isolation of costunohde and liriodenine with cytotoxic activities, along with the isolation of twenty-seven known compounds. The active costunohde existed as major constituent in this study.

Palavras-chave : Michelia compressa; Magnoliaceae; root wood; cytotoxicity.

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