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vol.54 issue4A FAST, ROBUST ELECTROCHEMICAL METHOD FOR THE AUTOMATED DETERMINATION OF HYDROGEN PEROXIDEDETERMINATION OF GABAPENTIN IN BULK DRUG AND IN PHARMACEUTICAL DOSAGE FORM BY HPLC METHOD author indexsubject indexarticles search
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Journal of the Chilean Chemical Society

On-line version ISSN 0717-9707

Abstract

CASTRO-CASTILLO, VICENTE; REBOLLEDO-FUENTES, MARCO  and  CASSELS, BRUCE K. SYNTHESIS OF A-RING-SUBSTITUTED 5,6,8,12B-TETRAHYDROISOINDOLO[1,2-A]ISOQUINOLIN-8-ONES. J. Chil. Chem. Soc. [online]. 2009, vol.54, n.4, pp.417-423. ISSN 0717-9707.  http://dx.doi.org/10.4067/S0717-97072009000400021.

The synthesis of 4,5,8,12b-tetrahydroisoindolo[1,2-a]isoquinolin-8-ones is reviewed The unsubstituted parent compound, a series of fourteen A-ring-substituted derivatives, most of them new, and some of their doubly benzylic, 12b-hydroxylated oxidation products were synthesized. Unusual features of their reactivity are briefy discussed.

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