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Journal of the Chilean Chemical Society

On-line version ISSN 0717-9707

Abstract

NARENDER, ATMAKURI; LAXMINARAYANA, E  and  THIRUMALA CHARY, M. A NOVEL SYNTHESIS OF SUBSTITUTED 4-HYDROXY- 1,8-NAPHTHYRIDINES. J. Chil. Chem. Soc. [online]. 2009, vol.54, n.4, pp.473-474. ISSN 0717-9707.  http://dx.doi.org/10.4067/S0717-97072009000400033.

Michael addition of 2-aminopyridines with methylpropiolate to afforded the addition compound 1a-g, which on further cyclisation at higher temperature in dowtherm-A to yield cyclised product 2 a-g, with respective yields depends on the nature of the substituents.

Keywords : Propionoic acid methyl ester; 2-aminopyridine and 3-(Pyridin-2-ylamino)-acrylic acid methyl ester.

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