SciELO - Scientific Electronic Library Online

 
vol.55 issue4SYNTHESIS, CHARACTERIZATION AND PRELIMINARY CATALYTIC PROPERTIES OF NEW COPPER (I) COMPLEXE [Cu (pyrazolyl)2]X TYPEA PRELIMINARY STUDY OF THE DISTRIBUTION AND MOBILITY OF MERCURY IN WATER AND SEDIMENTS FROM THE SAN JUAN RIVER WATERSHED, NUEVO LEON MEXICO author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

Share


Journal of the Chilean Chemical Society

On-line version ISSN 0717-9707

Abstract

JAYACHANDRA REDDY, B  and  SOMASEKHARA REDDY, M.C. SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL EVALUATION OF FEW 2, 3-SUBSTITUTED QUINOXALINES. J. Chil. Chem. Soc. [online]. 2010, vol.55, n.4, pp.483-485. ISSN 0717-9707.  http://dx.doi.org/10.4067/S0717-97072010000400016.

The quinoxaline derivatives (i-v) were synthesized through cyclization-oxidation of a- bromo carbonyl compounds with o-phenyl diamines (7a and 10a) and further coupling at 6-position via Suzuki reaction using PdCl2 (dppf).DCM, ter. BuNH2, Na2CO3 in IPA, H2O refluxed for 16 h. As the results of antibacterial screening tests done by paper disc method, quinoxaline derivatives (i) and (v) revealed significant inhibition zone on Bacillus spericus and quinoxaline derivatives (iii) and (v) on Escherichia coli cultures.

Keywords : Quinoxaline; Suzuki; Coupling; microwave; Bacillus spericus; Escherichia coli.

        · text in English     · English ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License