SciELO - Scientific Electronic Library Online

 
vol.61 issue3RAMAN IDENTIFICATION OF PIGMENTS IN THE WORK OF THE CHILEAN CONTEMPORARY VISUAL ARTIST IGNACIO GUMUCIOSYNTHESIS, ANTI-PHYTOPATHOGENIC AND DPPH RADICAL SCAVENGING ACTIVITIES OF C-PRENYLATED ACETOPHENONES AND BENZALDEHYDES author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • On index processCited by Google
  • Have no similar articlesSimilars in SciELO
  • On index processSimilars in Google

Share


Journal of the Chilean Chemical Society

On-line version ISSN 0717-9707

Abstract

HEYDARI, ROUHOLLAH  and  MOUSAVI, MASOUMEH. SIMULTANEOUS DETERMINATION OF SACCHARINE, CAFFEINE, SALICYLIC ACID AND BENZOIC ACID IN DIFFERENT MATRIXES BY SALT AND AIR-ASSISTED HOMOGENEOUS LIQUID-LIQUID EXTRACTION AND HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY. J. Chil. Chem. Soc. [online]. 2016, vol.61, n.3, pp.3090-3094. ISSN 0717-9707.  http://dx.doi.org/10.4067/S0717-97072016000300017.

Saccharine, caffeine, salicylic acid and benzoic acid were extracted and quantified simultaneously by coupling the salt and air-assisted homogeneous liquid-liquid extraction (SAAHLLE) technique with high-performance liquid chromatography (HPLC). Various parameters such as extraction solvent and its volume, salt and its concentration, volume of injected air, vortex time and sample pH were evaluated and optimized. Analytical parameters of the proposed method were determined under the optimized conditions. The calibration curves showed good linearity in the range of 5-100 μg/mL for saccharine, caffeine, salicylic acid and benzoic acid. The limit of detection (LOD) values for saccharine, caffeine, salicylic acid and benzoic acid were 0.024, 0.013, 0.0048 and 0.0052 ng/mL, respectively. The recoveries were in the range of 88.0-94.0% with RSD values ranging from 3.8 to 6.8%.

Keywords : Homogeneous liquid-liquid extraction; salt and air-assisted; saccharine; caffeine; salicylic acid; benzoic acid; high-performance liquid chromatography.

        · text in English     · English ( pdf )

 

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License