SciELO - Scientific Electronic Library Online

 
vol.20 número2Evaluación de Esteroides Aromáticos como Indicadores de Madurez Térmica en Extractos de RocaEvaluación del Poder Antioxidante de Fracciones de Aceite Esencial Crudo de Schinus molle L. obtenidas por Destilación al Vacío índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

Links relacionados

Compartir


Información tecnológica

versión On-line ISSN 0718-0764

Resumen

CORTES-ROJO, Christian; ESTRADA-VILLAGOMEZ, Mirella; MANZO-AVALOS, Salvador  y  SAAVEDRA-MOLINA, Alfredo. Influence of Lipoperoxidation over Mitochondrial Oxidative Damage and Integrity of Saccharomyces cerevisiae. Inf. tecnol. [online]. 2009, vol.20, n.2, pp.71-81. ISSN 0718-0764.  http://dx.doi.org/10.4067/S0718-07642009000200010.

The influence of lipoperoxidation over mitochondrial oxidative damage and integrity of Saccharomyces cerevisiae has been studied. For this, the unsaturation degree of cell membranes from Saccharomyces cerevisiae was increased by adding α-linolenic acid (C18:3). Spheroplasts were obtained to evaluate in situ the mitochondrial function. Lipid peroxidation levels, stimulated by the treatment with Fe2+, increased only in spheroplasts with C18:3, while mitochondrial function, measured as cyanide-sensitive oxygen consumption, and cell integrity, determined by trypan blue exclusion, were affected significatively only in spheroplasts with C18:3. These results show that lipid peroxidation sensitizes cell integrity and mitochondrial function towards damaging effects of oxidative stress.

Palabras clave : Saccharomyces cerevisiae; oxidative stress; linolenic acid; lipid peroxidation.

        · resumen en Español     · texto en Español     · Español ( pdf )

 

Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons