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Información tecnológica

On-line version ISSN 0718-0764

Abstract

SANTAFE, Gilmar G; GUZMAN, Miguel S  and  TORRES, Omar L. HOLOSTAN-TYPE TRITERPENE WITH ANTIFUNGAL ACTICVITY OBTAINED FROM THE SEA CUCUMBER HOLOTHURIA FLORIDANA: COLLECTED IN THE CISPATÁ BAY, CÓRDOBA-COLOMBIA. Inf. tecnol. [online]. 2014, vol.25, n.2, pp.87-92. ISSN 0718-0764.  http://dx.doi.org/10.4067/S0718-07642014000200010.

This is the first time that the compounds holosta-22,25-epoxi-7,9-dien-3β-ol (compound 1) and holosta-22,25-epoxi-7,9-dien-17-3β-diol (compound 2) are obtained, in free form, from the sea cucumber Holothuriafloridana, collected in the Cispatá Bay in the Colombian Caribbean. Sea cucumbers of the Holothuria genus are known as sources of biologically active glycosylated triterpenes. Compounds 1 and 2 were isolated and purified via chromatographic processes and chemically characterized by using combined techniques of liquid chromatography coupled with mass spectrometry (QSTAR Elite LC/MS) in addition to proton and carbon 13 nuclear magnetic resonance experiments. The compounds obtained were evaluated for their fungicide activity against the phytopathogenic fungus Sclerotiniasclerotiorum, finding promising results in compound 2.

Keywords : sea cucumber; Holothuria floridana; holostan-typetriterpenes; fungicideactivity; CispatáBay.

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