SciELO - Scientific Electronic Library Online

 
vol.68 número6Reparación laparoscópica de hernia de Morgagni en un adulto: reporte de casoCirugía profiláctica en síndrome de cáncer hereditario de mama índice de autoresíndice de materiabúsqueda de artículos
Home Pagelista alfabética de revistas  

Servicios Personalizados

Revista

Articulo

Indicadores

Links relacionados

  • En proceso de indezaciónCitado por Google
  • No hay articulos similaresSimilares en SciELO
  • En proceso de indezaciónSimilares en Google

Compartir


Revista chilena de cirugía

versión On-line ISSN 0718-4026

Resumen

VILA BLANCO, Julio Miguel  y  NABHAN, Said. Merkel cell carcinoma: Report on 3 patients. Rev Chil Cir [online]. 2016, vol.68, n.6, pp.456-461. ISSN 0718-4026.  http://dx.doi.org/10.1016/j.rchic.2016.04.001.

Aim: Our purpose was to report on three patients having Merkel cell carcinoma (MCC). This tumor is a trabecular carcinoma or undifferentiated small cell carcinoma of the skin. It represents a rare and well-defined characteristic neoplasm, associated with radiation, immunosuppression and recently with the polyomavirus. Material and methods: Descriptive clinical study of three adult patients treated between 2011 and 2013 in our center either in the General Surgery Department or Oral Surgery Department. There were two men (50 and 79 years) and one woman (79 years). Results: The youngest man presented with a right inguinal lymph node. The primary lesion was not found. The second male patient had been on infliximab therapy due inflammatory bowel disease and had a lesion on the inferior lip. The single female patient had a right pretibial lesion. Diagnosis was made by means of immunohistochemical analysis of biopsies (CAM 5.2 and CK-20 positive, TTF-1 negative, chromogranin and NSE positive intermediate 2 and 1). In all three cases surgery and sentinel node technique was performed. After surgery, treatment was continued with adjuvant chemotherapy in two patients. Radiotherapy was applied to the patient who had been on infliximab therapy. This patient ultimately died. Conclusions: MCC is a rare tumor. It occurs in adult patients with distinct clinical features. It has to be suspected to allow an early diagnosis. Diagnosis is made by biopsy and it is confirmed by immunohistochemistry. Surgery with the sentinel node technique is the usual treatment, besides adjuvant chemoradiotherapy it is also applied.

Palabras clave : Merkel cell carcinoma; Neuroendocrine carcinoma; Skin trabecular carcinoma.

        · resumen en Español     · texto en Español     · Español ( pdf )

 

Creative Commons License Todo el contenido de esta revista, excepto dónde está identificado, está bajo una Licencia Creative Commons