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Revista de otorrinolaringología y cirugía de cabeza y cuello

versión On-line ISSN 0718-4816

Resumen

CONTRERAS R, Pilar; MUNOZ S, Daniel; CONTRERAS R, José  y  RAHAL E, Maritza. Time to initiation of postoperative radiotherapy as a prognostic factor in patients with advanced laryngeal cancer. Rev. Otorrinolaringol. Cir. Cabeza Cuello [online]. 2018, vol.78, n.4, pp.406-412. ISSN 0718-4816.  http://dx.doi.org/10.4067/s0717-75262018000400406.

Introduction:

Among the factors that play a role in the survival and recurrence of disease of patients with operated squamous laryngeal cancer is the time to initiation of postoperative radiotherapy (RT).

Aim:

To determine the impact of delayed onset of postoperative RT on survival and disease recurrence in patients with advanced operated squamous laryngeal cancer.

Material and Method:

Retrospective cohort study. Collection of data through review of clinical records. Analysis of survival and disease recurrence using the Kaplan-Meier method, comparison of curves with Log-Rank test and Cox regression model for analysis of prognostic factors.

Results:

The waiting time between surgery and the initiation of RT in our hospital realities was 11 weeks. The 5-year specific survival in patients who start RT ≤ 6 weeks after surgery is 33.3% and decreases to 20% in those who start > 6 weeks (p = 0.20).

Conclusion:

Patients who start RT in more than 6 weeks after surgery do not present a statistically significant difference in prognosis.

Palabras clave : Squamous laryngeal cancer; postoperative radiotherapy; time to initiation of radiotherapy; delay; survival.

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