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Revista chilena de cardiología

On-line version ISSN 0718-8560


ALFARO, Mario et al. Dipyridamol Stress Echocardiography and Non-invasive Coronary Reserve: Preliminary report. Rev Chil Cardiol [online]. 2013, vol.32, n.2, pp.111-116. ISSN 0718-8560.

Background: Stress Echocardiography is a common technique in the study of patients with known or suspected Coronary artery disease (CAD). Recently the vasodilation test has been recommended for the non invasive study of Coronary Flow Reserve (CFR). Aim: to report our preliminary experience with Di-pyridamol Stress Echocardiography (DSE), an initial follow-up, and the study of CFR in the distal portion of the left anterior descending coronary artery (LAD). Methods: 164 consecutive patients (101 men, mean age 65) with suspected or known CAD underwent a high-dose DSE (0.84 mg/kg over 6 min) between July 2011 and September 2012. The test included a study of CFR. All patients completed the test within 25 min. Prospective follow-up regarding major adverse cardiovascular events(revascularization, cardiac mortality and infarction) was conducted for a mean of 10 months (range 6-18) Results: DSE was positive for ischemia in 34 (21%) patients, showed abnormal wall motion in 19 (12%), abnormal CFR in 29 (15%) , and both abnormalities in12 (7%). 142 patients (88%) had a normal CFR in the LAD. 151 patients were followed for a mean of 10 months (6 to 18). Ten of these patients required some type of revascularization. There were no myocardial infarctions or cardiac deaths. Due to the short follow up period and the low incidence of events, it was not possible to estimate the predictive value of abnormal CFR. Conclusion: The dipyridamol echo stress test with a study of coronary flow reserve is safe and brief. The predictive value for cardiac events remains to be determined.

Keywords : Dipirydamol; Stress echocardiography; coronary flow reserve; non invasive test.

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