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Revista chilena de cardiología

On-line version ISSN 0718-8560


STOCKINS, Benjamín et al. Association between metabolic disease and the severity of coronary artery disease measured by Gensini Score. Rev Chil Cardiol [online]. 2014, vol.33, n.3, pp.181-188. ISSN 0718-8560.

Introduction: The association between coronary artery (CAD) and dysglicemia is well established. Diabetes (DM) is recognized as one of the most important coronary risk factors, but the association of CAD and metabolic syndrome (MS) is less well defined. Our objective was to evaluate the degree of coronary atherosclerotic disease in relation to the presence of MS and DM . Patients and Method: The data of 413 patients electively studied with coronary angiography over a period of one year was analyzed. Patients were divided into three groups: Patients with DM, patients with MS (without DM) and patients without a metabolic disorder (no DM, no MS). The severity of CAD was measured by the Gensini Score. Results: Mean age was 63,8 ±11,17 years. The prevalence of patients with MS was 38% (n=158), with DM 45% (n=186) and without a metabolic disorder 17% (n=69). The global prevalence of CAD was 52,7%. The prevalence of CAD in the different groups was as follows: Absence of metabolic disease 33.9%, patients with MS 52.2% and patients with DM 62.2% (p< 0.001). Conclusions: This observational study suggests that, compared to subjects without metabolic disease, the prevalence and severity of CAD are higher in patients with MS and even higher in patients with DM

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