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Revista chilena de cardiología

On-line version ISSN 0718-8560

Abstract

ANINAT, Mauricio. Degree of stenosis and vulnerability of coronary artery lesions. Rev Chil Cardiol [online]. 2016, vol.35, n.2, pp.177-182. ISSN 0718-8560.  http://dx.doi.org/10.4067/S0718-85602016000200013.

Coronary angiography has long been and is still the basic method for deciding coronary interventions, and the severity of stenosis remains the main prognostic marker of the disease. However, plaque vulnerability does not appear to be associated with a greater degree of angiographic stenosis, which is not consistent with histopathological findings or with physiological assessment of ischemia-producing lesions. The purpose of this article is to briefly review this controversy while suggesting that plaques vulnerability correlate with the degree of anatomical and functional stenosis, and to describe the potential mechanism that could determine this vulnerability as well as to give likely explanations that reconcile angiographic findings with histopathological and functional observations.

Keywords : Coronary angiography; myocardial ischemia; coronary artery stenosis; atherosclerosis; plaque.

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