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Revista chilena de cardiología

On-line version ISSN 0718-8560


ECHEVERRIA, Guadalupe  and  RIGOTTI, Attilio. Mediterranean Diet and HDL. Rev Chil Cardiol [online]. 2017, vol.36, n.2, pp.136-143. ISSN 0718-8560.

Levels, lipid and protein composition, and functional properties of high density lipoproteins (HDL) determine the biological functions of this lipoprotein fraction and its protective role in cardiovascular disease. These HDL-related parameters can be modulated by pharmacological and non-pharmacological interventions. In the last two decades, it has been established that consumption of Mediterranean diet, especially when supplemented with extra virgin olive oil, improves different quantitative parameters (cholesterol levels and number of particles, as well as particle size) and functional properties (cell cholesterol efflux, cholesterol esterification as well as antioxidant, endothelial relaxation, and anti-inflammatory activities) of HDL in humans. Most likely, these effects contribute to the widely demonstrated benefits of Mediterranean diet intake against different chronic diseases.

Keywords : Mediterranean Diet; HDL; cardiovascular disease.

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