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Revista clínica de periodoncia, implantología y rehabilitación oral

versão On-line ISSN 0719-0107


MILLONES-GOMEZ, Pablo  e  AGUILAR, Alberto Aguirre. Efficacy of azithromycin associated with scaling and root planing in chronic periodontitis. Rev. Clin. Periodoncia Implantol. Rehabil. Oral [online]. 2017, vol.10, n.1, pp.33-37. ISSN 0719-0107.


To evaluate the efficacy of azithromycin associated with the RAR (scaling and root planing) in patients with chronic periodontitis.

Material and Methods:

This clinical trial parallel randomized, controlled, triple blind, was developed in the Stomatology Clinic of the Catholic University Los Angeles of Chimbote (Trujillo, Peru), between March and December 2015. The participants were 30 adult patients randomized 2 groups, designated by the letters A and B of 15 members each. Each patient was evaluated periodontally before Give you the scaling and root planing and optimization hygiene techniques. Patients in group A, were prescribed antibiotic treatment with azithromycin 500 mg orally every 24 hours for 3 days. While, group B were prescribed a placebo with the same physical characteristics of the antibiotic chosen. Patients were evaluated at 3, 4 and 5 months. The efficacy was evaluated using the Student t test to compare means, considering a level of significance for the values of p <0.05.


It was found that both groups were able to improve probing depth and clinical attachment level however no statistically significant differences between them.


Azithromycin associated with the RAR is not effective as adjunctive therapy in patients with chronic periodontitis.

Palavras-chave : Azithromycin; scaling and root planing; chronic periodontitis.

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