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Revista clínica de periodoncia, implantología y rehabilitación oral
versión On-line ISSN 0719-0107
Resumen
PRINCIPE-DELGADO, Yuliana; MALLMA-MEDINA, Adrián y CASTRO-RODRIGUEZ, Yuri. Effectiveness of fibrin-rich plasma and collagen membrane in guided bone regeneration. Rev. Clin. Periodoncia Implantol. Rehabil. Oral [online]. 2019, vol.12, n.2, pp.63-65. ISSN 0719-0107. http://dx.doi.org/10.4067/S0719-01072019000200063.
Aim:
of this study was to determine the effectiveness of two biomaterials, fibrin-rich plasma (PRF) and collagen membrane in guided bone regeneration.
Materials and method:
Thirty male guinea pigs were used, weighing between 900 and 1100 g., divided into three groups of 10 guinea pigs each (Group A: control, group B: collagen membrane and group C: fibrin-rich plasma). Each group had a 2-mm unilateral mandibular bone defect. Group A did not receive any biomaterial; in groups B and C the biomaterials were used in the bone defects. After 15 and 30 days of healing, histological sections were performed to evaluate the amount of fibroblasts, osteocytes and osteoblasts.
Results:
After 15 days, group C formed 40.6 ± 8.08 osteocytes / camp and group B 27.6 ± 4.72 (p <0.05); After 30 days, group C: 30.6 ± 11.55 and group B: 23.6 ± 3.85 (p> 0.05).
Conclusion:
During the first 15 days of healing, PRF induces a greater cellular proliferation than the other groups in a significant way; after 30 days, the proliferation is similar to the collagen membrane group without significant differences.
Palabras clave : Bone regeneration; Fibrin; Collagen; Guinea pigs.